Vitamin C: Best known as an antioxidant, but it also works with various enzymes in the body. In relation to Growth Hormone (GH), Vitamin C acts as a co-factor in the activity of an enzyme called Peptidylglycine Alpha-Amidating Monooxygenase, or PAM, which activates various neuropeptides, or brain proteins. PAM exists in large amounts in both the hypothalamus of the brain, where Growth-Hormone-Releasing Hormone (GHRH) is produced, and the pituitary gland, where GH is produced. The thought is that vitamin C, through its actions on PAM, activates Growth-Hormone-Releasing Hormone from the hypothalamus, which then triggers the release of GH from the pituitary gland.
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